A double-blind, randomized controlled trial on the effectiveness and safety of 15% malunggay ointment (Moringa oleifera) vs 2% mupirocin ointment in treating localized pyoderma
Journal of the Philippine Dermatological Society
;
: 11-18, 2016.
Article
in English
| WPRIM
| ID: wpr-633143
ABSTRACT
BACKGROUND:
Superficial bacterial infection is among the most common reasons for dermatologic consult. Numerous published articles suggest that the dried leaf of malunggay exhibits antibacterial property.OBJECTIVES:
To compare the effectiveness and safety of 15% malunggay ointment with 2% mupirocin ointment in treating localized pyoderma.METHODS:
Sixty-three patients with localized pyoderma (?10% of total body surface area) were enrolled in this randomized, double-blind study to apply either 15% malunggay or 2% mupirocin ointment twice daily for 14 days. Clinical evaluation using the Global Assessment Score (GAS) for pruritus, pain, erythema, vesiculation, moistness and crusting were conducted at baseline and days 3, 7 and 14 of clinic visit.RESULTS:
Both malunggay and mupirocin groups showed significant decreases in GAS from baseline to days 3, 7 and 14 of treatment (p=0.000, Repeated measures, ANOVA). By days 7 and 14, median GAS of malunggay ointment was higher than mupirocin (1 vs. 0, pCONCLUSION:
Patients in the mupirocin treatment arm had significantly lower global assessment scores and higher cure rates compared to those in the malunggay treatment arm.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Ointments
/
Pain
/
Pruritus
/
Pyoderma
/
Bacterial Infections
/
Mupirocin
/
Erythema
/
Ambulatory Care
/
Anti-Bacterial Agents
Type of study:
Controlled clinical trial
Limits:
Adult
/
Child
/
Female
/
Humans
/
Male
Language:
English
Journal:
Journal of the Philippine Dermatological Society
Year:
2016
Type:
Article
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