Risk factors for community acquired methicillin resistant Staphylococcus aureus infections among 0-18 yrs old: A retrospective case- control study
Pediatric Infectious Disease Society of the Philippines Journal
;
: 38-47, 2014.
Article
in English
| WPRIM
| ID: wpr-633483
ABSTRACT
@#<p style="text-align justify;"><strong>BACKGROUND:
</strong> Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infection is an emerging health problem in pediatrics. Risk factors are not well established in children.<br />OBJECTIVE:
To determine the risk factors for the development of methicillin-resistant Staphylococcus aureus infections arising in the community.<br /><strong>METHODOLOGY:
</strong> A restrospective case-control study was performed from January 2004 to December 2011. Cases included patients who were culture positive for Staphylococcus aureus and resistant to methicillin/oxacillin while Control included patients who were sensitive to methicillin/oxacillin. The study identified and analyzed the epidemiology, risk factors and resistance pattern of CA-MRSA isolates.<br /><strong>RESULTS:
</strong> Three hundred twety three (323) patients with Staphylococcus aureus infections were enrolled 172 were CA-MRSA infections (cases); and 151 were community acquired methicillin-sensitive Staphylococcus aureus (CA-MSSA) infections (control). Demographic characteristics and clinical profile were skin (cellulitis, furunculosis and abscess) and pulmonary (pneumonica and empyema). The survival rate was high for both groups (>90%). The final multivariate logistic regresion model showed that level of crowding and socio-economic status remained model showed that level of crowding and socio-economic status remained as risk factors for CA-MRSA. The odds of having CA-MRSA in crowded households is 0.35 (90%CI 0.20-0.62) less likely when compared to the odds of acquiring MRSA in less crowded households (p=0.003). Those who had low socio-eonomic had 2.49 times higher chance (90%CI; 1.39 -4.47) of aquiring CA-MRSA compared to those with higher socio-economic status (p=0.01).<br /><strong>CONCLUSION:
</strong> CA-MRSA is an emerging problem. This warrants recognition of patients with significant risk factors such as low socio-economic status and level of crowding. This may serve guide in choosing the appropriate antimicrobial theraply.</p>
Search on Google
Index:
WPRIM (Western Pacific)
Main subject:
Oxacillin
/
Staphylococcal Infections
/
Community-Acquired Infections
/
Methicillin-Resistant Staphylococcus aureus
/
Furunculosis
/
Methicillin
/
Anti-Infective Agents
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adolescent
/
Child
/
Female
/
Humans
/
Infant
/
Male
Language:
English
Journal:
Pediatric Infectious Disease Society of the Philippines Journal
Year:
2014
Type:
Article
Similar
MEDLINE
...
LILACS
LIS