Recurrent hydatidiform mole with NLRP7 mutation: The first confirmed case in the Philippines / Philippine Journal of Obstetrics and Gynecology
Philippine Journal of Obstetrics and Gynecology
;
: 27-32, 2017.
Article
in English
| WPRIM
| ID: wpr-633540
ABSTRACT
High gravidity hydatidiform mole (HM) without normal pregnancy is very rare. The challenge of managing such cases will dwell on the concern of having normal conception versus having another molar gestation and its neoplastic sequelae. Presented in this paper is a case of a 32-year-old, gravida 5 para 0 (0040) who was admitted for the management of her fifth molar pregnancy. She underwent suction curettage and administration of methotrexate chemoprophylaxis. Genetic testing was done, which revealed a homozygous mutation in NLRP7, the gene implicated in recurrent molar gestations. This paper discusses the proper approach to determine the cause of recurrent molar pregnancies, as well as the management and prognosis of such cases.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Vacuum Curettage
/
Hydatidiform Mole
/
Genetic Testing
/
Methotrexate
/
Chemoprevention
/
Gravidity
/
Homozygote
/
Molar
/
Mutation
Type of study:
Prognostic study
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
Philippine Journal of Obstetrics and Gynecology
Year:
2017
Type:
Article
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