Specimen handling and tissue preaparation in pre-analytical phase of HER2 testing at tertiary referral hospitals of Metro Manila
Acta Medica Philippina
;
: 48-53, 2015.
Article
in English
| WPRIM
| ID: wpr-633568
ABSTRACT
INTRODUCTION:
HER2 test result depends on a good quality histological section of the breast specimen. Laboratories that process specimens using sophisticated and molecular testing should receive suitable specimen for more accurate results and less waste of expensive resources.METHODS:
A questionnaire based on the ASCO-CAP Guidelines for HER2 testing was developed and administered to pathologists from the local laboratories of Metro Manila-Philippines tertiary referral hospitals. Questionnaire responses were analyzed using descriptive statistics.RESULTS:
Most laboratories did quality control/quality assessment monitoring for the pre-analytic, analytic,post-analytic and turn¬around time phases. Many transported their specimens from the operating room to the laboratoryCONCLUSION:
Even in standardized procedures, small variations in sample processing for IHC and FISH can still occur. Inexperienced laboratories will have greater problems interpreting HER2 status results. Laboratories should look into their system in handling specimens for an accurate HER2 testing towards quality assurance.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Quality Control
/
Breast
/
Surveys and Questionnaires
/
Pathologists
/
Laboratories
Type of study:
Qualitative research
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Acta Medica Philippina
Year:
2015
Type:
Article
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