Pathogenesis and Associated Diseases of Kaposi's Sarcoma-associated Herpesvirus / 中国病毒学
Virologica Sinica
;
(4): 248-255, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-634197
ABSTRACT
Kaposi's sarcoma-associated herpesvirus (KSHV) is the primary etiological agent of Kaposi's sarcoma, primary effusion lymphoma and muticentric Castleman's disease. In common with the other herpesviruses, KSHV exhibits both latent and lytic life cycles, both of which are characterized by distinct gene expression profiles and programs. KSHV encodes proteins which play essential roles in the inhibition of host adaptive and innate immunity, the inhibition of apoptosis, and the regulation of the cell cycle. KSHV also encodes several proteins which have transforming and intrcellular signalling activity.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
Language:
Chinese
Journal:
Virologica Sinica
Year:
2007
Type:
Article
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