Clinical treatment of idiopathic orbital inflammatory pseudotumor / 中华实验眼科杂志

ABSTRACT

Idiopathic orbital inflammatory pseudotumor (IOIP) is a common ophthalmic disease with uncertain etiology and pathogenesis.It charactarized by chronic inflammatory cell infiltration and connective tissue proliferation.At present,its clinical treatments mainly include pharmacotherapy,radiation therapy and surgery,and the primary treating drugs include glucocorticosteroids and immunosuppressive agents.The mainstay of therapy is systemic glucocorticosteroids,although there is an increasing trend toward the use of alkylating agents,antimetabolites,monoclonal antibodies and other immunosuppressive agents.The progress in clinical treatment of IOIP was reviewed.