Reduced Cortical Thickness in Patients with Late Life Depression without Cerebral Vascular Disease
Journal of Korean Geriatric Psychiatry
;
: 97-100, 2015.
Article
in Korean
| WPRIM
| ID: wpr-63674
ABSTRACT
OBJECTIVES:
The aim of this study is to compare cortical thickness in late life major depression patients without cerebral vascular disease (CVD) with that of non-depressed normal comparison subjects using magnetic resonance imaging (MRI).METHODS:
Altogether, 47 subjects were finally recruited from the Memory impairment clinics of Pusan National University Hospital in Korea. All subjects (late life major depression patients without CVD n=21, matched non-depressed normal comparisonsubjects:
n=26) underwent 3-tesla MRI.RESULTS:
Late life major depression patients without CVD showed reduced cortical thickness in left precuneus, left inferior temporal gyrus, and left cuneus compared with non-depressed normal comparison subjects.CONCLUSION:
Our findings suggest that late life major depression without CVD is associated with reduced cortical thickness.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Vascular Diseases
/
Magnetic Resonance Imaging
/
Depression
/
Korea
/
Memory
Limits:
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Journal of Korean Geriatric Psychiatry
Year:
2015
Type:
Article
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