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Clinical value of coronal plane reformatted with three-dimensional ultrasound in differential diagnosis of benign and malignant breast solid masses / 中华医学超声杂志(电子版)
Article in Chinese | WPRIM | ID: wpr-636777
Responsible library: WPRO
ABSTRACT
Objective To evaluate the clinical value of the coronal plane of three-dimensional ultrasonography in the diagnosis of breast cancer. Methods Ninety-seven patients with 106 solid breast lesions were analyzed retrospectively. Two-dimensional images were evaluated with breast imaging reporting and data system for ultrasonography (BI-RADS-US) classification and were compared with pathological results. The value of two-dimensional ultrasound in the differentiation of benign and malignant lesions of breast lesions was evaluated. The ultrasonographic features on three-dimensional coronary plane of breast benign or malignant masses were analyzed by multiple stepwise binary logistic regression analysis. Receiver operating characteristic (ROC) curve was drawn and the areas under curves were calculated to evaluate the ability of regression model in diagnosis of benign and malignant breast lesions. Results The pathological results revealed that 106 lesions were consisted of 71 breast cancers and 35 benign neoplasms. The diagnostic accuracy, sensitivity and speciifcity were 85.8%, 84.5%and 88.6%respectively. Two ultrasonic features which were finally applied into the Logistic regression model were angulation or spiculation and′sun-like symptom′. The area under the ROC curve was 0.899, the standard error was 0.033, and the 95%conifdence interval was between 0.834 and 0.965. The logistic regression model could be useful for classiifcation of benign and malignant breast masses. The diagnostic accuracy was 88.7%(94/106), sensitivity was 90.1%(64/71), speciifcity was 85.7%(30/35), positive predictive value was 92.8%(64/69) and negative predictive value was 81.1%(30/37) respectively. Conclusions The coronal plane of breast three-dimensional, especially angulation or spiculation and′sun-like symptom′have an important value in the differential diagnosis of benign and malignant breast lesions. For complicated lesions, three-dimensional ultrasound coronal plane is helpful to improve the doctor′s diagnosis conifdence.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Medical Ultrasound (Electronic Edition) Year: 2014 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Medical Ultrasound (Electronic Edition) Year: 2014 Type: Article