Oxidative stress - mitochondrial dysfunction and the relationship with retinal ganglion cell apoptosis / 国际眼科杂志(Guoji Yanke Zazhi)
International Eye Science
;
(12): 238-241, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-637172
ABSTRACT
Mitochondria play an important role in energy ( ATP ) production through oxidative phosphorylation pathway and the regulation of cell death by apoptosis. Mitochondrial dysfunction has been implicated in the pathophysiology of a number of neurodegenerative diseases. Glaucoma as a neurodegenerative disorder, mitochondrial oxidative stress in the pathogenesis of glaucoma and the damage of RGCs has received close attention in recent years. ln this article, we reviewed the current evidences and recent advances in the relationship between mitochondrial oxidative stress and the RGCs apoptosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Eye Science
Year:
2015
Type:
Article
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