Treatment for traumatic optic neuropathy with mouse nerve growth factor:a meta-analysis / 国际眼科杂志(Guoji Yanke Zazhi)
International Eye Science
; (12): 633-635, 2015.
Article
in Zh
| WPRIM
| ID: wpr-637255
Responsible library:
WPRO
ABSTRACT
AIM:
To evaluate the efficacy of treating traumatic optic neuropathy( TON) with mouse nerve growth factor.METHODS:
We searched the Cochrane Library, Pubmed, Medline, CNKI, Wanfang database and VIP to collect randomized controlled trials ( RCTs ) of using mouse nerve growth factor for TON. The quality of the included trials was assessed and poor-qualified trials were eliminated before the meta - analysis was conducted.RESULTS:
Seven RCTs with a total of 399 eyes included were retrieved, and OR=3. 78 with a 95%CI of [ 2. 35, 6.06], the difference was significant (PCONCLUSION:
The existing evidence supports that the prognosis of TON is better when mouse nerve growth factor are adopted in treatment, but there is still a need for well-planned, large-scale and multicenter RCTs to verify it.
Full text:
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Index:
WPRIM
Type of study:
Clinical_trials
/
Prognostic_studies
/
Systematic_reviews
Language:
Zh
Journal:
International Eye Science
Year:
2015
Type:
Article