Research advances on treatment of vitreomacular adhesion with gene recombinant ocriplasmin / 中华实验眼科杂志
Chinese Journal of Experimental Ophthalmology
;
(12): 1144-1147, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-637529
ABSTRACT
Vitreous retinal interface abnormalities are associated with many macular diseases.The main approach of treatment is to release the vitreomacular adhesion with pars plana vitrectomy.Because of its complication and limitation,researches of pharmacologic posterior vitreous detachment (PVD) were undertaken.Gene recombinant ocriplasmin was proved by several experiments and clinical trials by inducing a complete PVD,showing its promising prospect.This article reviewed the literatures of ocriplasmin,including pathobiology in treatment of vitreomacular adhesion,pharmacokinetics,vitreodynamics,experimental studies and clinical trials and adverse events.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Experimental Ophthalmology
Year:
2014
Type:
Article
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