Subependymal Giant Cell Astrocytoma Presenting with Tumoral Bleeding: A Case Report
Brain Tumor Research and Treatment
; : 37-41, 2017.
Article
in En
| WPRIM
| ID: wpr-63841
Responsible library:
WPRO
ABSTRACT
We report a rare case of subependymal giant cell astrocytoma (SEGA) associated with tumoral bleeding in a pediatric patient without tuberous sclerosis complex (TSC). A 10-year-old girl presented with a 2-week history of an increasingly aggravating headache. Brain magnetic resonance imaging revealed an approximately 3.6-cm, well-defined, heterogeneously enhancing mass with multistage hemorrhages on the right-sided foramen of Monro. The tumor was completely resected using a transcallosal approach. Intraoperatively, the mass presented as a gray-colored firm tumor associated with acute and subacute hemorrhages. The origin of the mass was identified as the ventricular septum adjacent to the foramen of Monro. A pathological analysis revealed pleomorphic multinucleated eosinophilic tumor cells with abundant cytoplasm. These cells showed positive staining for the glial fibrillary acidic protein and S100 protein. A diagnosis of SEGA was established. The patient recovered without any neurological symptoms. There was no evidence of TSC. The radiological follow-up showed no recurrence for 2 years. This was a case of SEGA with intratumoral hemorrhage, for which a favorable outcome was achieved, without any neurological deficit after tumoral resection.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Recurrence
/
Astrocytoma
/
Tuberous Sclerosis
/
Brain
/
Magnetic Resonance Imaging
/
Cerebral Ventricles
/
Follow-Up Studies
/
Cytoplasm
/
Diagnosis
/
Eosinophils
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Limits:
Child
/
Female
/
Humans
Language:
En
Journal:
Brain Tumor Research and Treatment
Year:
2017
Type:
Article