Analysis on Drug Resistance of Pathogenic Bacteria in Neonatal Hospital Infection / 实用儿科临床杂志

ABSTRACT

Objective To study the situation of pathogenic bacteria of neonate infection in hospital,so can guide clinical doctors use antibiotic rationally. Method The secretions of 159 neonates′ umbilous and eye matter orders were collected to be used as the specimen and the drug susceptibility experiment was done using MIC and K-B methods together in 159 neonates with hospital infection.Results One hundred and eighty-nine pathogenic bacterias were isolated from 1613 specimens.According to our materials,staphylococci aureus was the most important pathogenic bacteria,then staphylococci heamolyticus,staphylococci epidermidis,encherichia coli ,enterobater cloucac ,klebsiella pneumoniae.MRSA- positive rate was 52.6%,ESBLs-positive in E coli was 21%,inklebsiella pneumoniae was 20%.Drugs of sensitivity for Gram positive coccus were vancomycin(0) clindamycin(8.5%) cipnofloxacin(12.2%);the drugs of sensitivity for Gram negative ord were imipenem (4.4%),cipnofloxacin(5.3%),amikacin(12.7%).Conclusion It is instructive that use antibiotic rationally for controlling neonate infection in hospital.