Changes of Tumor Necrosis Factor - a and Souble Intercellular Adhesion Molecule - 1 in Serum and Cere-brospinal Fluid of Children with Viral Encephalitis / 实用儿科临床杂志
Journal of Applied Clinical Pediatrics
; (24)2003.
Article
in Zh
| WPRIM
| ID: wpr-638564
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WPRO
ABSTRACT
Objective To investigate the changes of tumor necrosis factor- ?(TNF- ?) and souble intercellular adhesion molecule - 1 (sICAM - 1) in serum and cerebrospinal fluid (CSF) in children with viral encephalitis (VE) before and after treatment,and to explore the pathogenesis of the cytokins in VE. Methods The levels of TNF - ? and sICAM - 1 in serum and CSF were determined before and after treatment using EL1SA in 38 children who were admitted with VE, and 20 children as normal controls. Results The levels of TNF- ? and sICAM - 1 in serum and CSF before treatment were obviously higher than those of control group,and the difference was significant(P 0. 05), but the serum and CSF TNF - ? and sICAM - 1 levels in SVE group were higher than those of control group(P
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Language:
Zh
Journal:
Journal of Applied Clinical Pediatrics
Year:
2003
Type:
Article