Influence of Inhaled Corticosteroids on Airway Transforming Growth Factor - ?1 Expression of Asthmatic Remodeling Model / 实用儿科临床杂志
Journal of Applied Clinical Pediatrics
;
(24)2003.
Article
in Chinese
| WPRIM
| ID: wpr-638581
ABSTRACT
Objective To investigate the role of inhaled corticosteroids (ICS) on transforming growth factor - ?1 (TGF - ?1 )of asthmatic remodeling model Methods One hundred and eight guinea pigs were divided into 3 groups randomly and equally asthmatic group( A), therapeutic group(B), control group(C) Three groups were treated by ovalbumin, budesonide, normal saline respectively The lung tissue specimens were collected after the guinea pigs were killed; the expression of TGF- ?1 was determined Results The expressions of TGF-?1 in A, K and C groups were(41 83 ? 10. 45) %, (27. 22 ? 8. 09)% , (15. 36 ? 2. 64)% respectively at 12 weeks. It was statistically significant( P
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Journal of Applied Clinical Pediatrics
Year:
2003
Type:
Article
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