Expression of Insulin-Like Growth Factor-Binding Protein-5 in Full-Term Rats with Hyperoxia-Induced Chronic Lung Diseases and Its Machanism / 实用儿科临床杂志
Journal of Applied Clinical Pediatrics
; (24)1986.
Article
in Zh
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| ID: wpr-639061
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ABSTRACT
Objective To investigate the expression of insulin-like growth factor-binding protein-5( IGFBP-5) in full-term rats with hyperoxia-induced chronic lung diseases(CLD) and its mechanism.Methods Ninety-six full-term rats were randomly exposed to hyperoxia (hyperoxia group)and room air(room air group).CLD was induced by hyperoxia exposure.RT-PCR and immunohistochemical metho -ds were used to detect the expression of IGFBP-5 at 1,3,7,10 ,14 and 21 days after exposure.Results The expression of IGFBP -5 was dynamic, the expression of IGFBP-5 increased significantly in hyperoxia group compared with room air group at 3 d to 10 d after hyperoxia exposure (P
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Language:
Zh
Journal:
Journal of Applied Clinical Pediatrics
Year:
1986
Type:
Article