Gaseous Signal Molecules and Pathogenesis of Pulmonary Artery Hypertension / 实用儿科临床杂志

ABSTRACT

The 4 kinds of gaseous signal molecules——nitric oxide,carbon monoxide,hydrogen sulfide and sulfur dioxide,which were discovered by people consecutively,all played significant pathophysiological roles in the cardiovascular system.With the pathogenesis of pulmonary artery hypertension(PAH) being illuminated uninterruptedly,gaseous transmitters and the interaction between them become the hot issue in the domain.This article summarized the mechanism of gaseous signal molecules in the formation process of PAH,in order to identify that during the morbidity process of PAH gaseous transmitters took effect in network regulating model.It also possessed great significance to comprehend the pathophysiological variation of PAH profoundly.