Expression and significance of HIF-1? and CXCR4 protein in tissues of breast cancer / 上海第二医科大学学报
Journal of Shanghai Jiaotong University(Medical Science)
;
(6)2006.
Article
in Chinese
| WPRIM
| ID: wpr-640809
ABSTRACT
Objective To investigate the expression of hypoxia-inducible factor-1?(HIF-1?) and chemokine receptor 4(CXCR4) protein in tissues of breast cancer and its association with clinicopathological features.MethodsThe expression of HIF-1? and CXCR4 protein in 60 breast cancer,30 breast fibroadenoma and 20 normal breast samples were detected by immunohistochemistry,and the relationship between the expression of HIF-1? and CXCR4 protein in the tissues of breast cancer and its association with clinicopathological factors were analysed.ResultsThere was no positive expression of HIF-1? and CXCR4 protein in normal breast tissues.The positive expression rates of HIF-1? protein in tissues of breast cancer and breast fibroadenoma were 65.0% and 26.7%,respectively(P
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Shanghai Jiaotong University(Medical Science)
Year:
2006
Type:
Article
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