Acute Lymphoblastic Leukemia Manifesting as Acute Vogt-Koyanagi-Harada Disease
Korean Journal of Ophthalmology
; : 325-328, 2009.
Article
in En
| WPRIM
| ID: wpr-64096
Responsible library:
WPRO
ABSTRACT
We describe a case of bilateral exudative retinal detachment associated with prodromal symptoms simulating the presentation of acute Vogt-Koyanagi-Harada disease that was eventually diagnosed as acute lymphoblastic leukemia. A 42-year-old man presented with sudden visual loss in both eyes for two weeks. He complained of intermittent headache, neck stiffness and tinnitus for a month. His best-corrected visual acuities were 20/200 in both eyes. Fluorescein angiography, optical coherence topography and indocyanine green angiography featured bilateral serous retinal detachments. A clinical diagnosis of incomplete type Vogt-Koyanagi-Harada disease was considered. However, complete blood cell count showed a marked increase in the number of white blood cells and bone marrow examination revealed precursor B cell lymphoblastic leukemia. The patient started on induction chemotherapy. A week later, his best-corrected visual acuities were 20/25 and the serous retinal detachments were nearly absorbed in both eyes. Bilateral exudative retinal detachment associated with neurologic and auditory abnormalities may be a presenting sign of acute lymphoblastic leukemia. Clinicians should be aware of the possibility of leukemia in such patients.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Retinal Detachment
/
Fluorescein Angiography
/
Visual Acuity
/
Uveomeningoencephalitic Syndrome
/
Follow-Up Studies
/
Tomography, Optical Coherence
/
Diagnosis, Differential
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Precursor Cell Lymphoblastic Leukemia-Lymphoma
/
Fundus Oculi
Type of study:
Diagnostic_studies
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Observational_studies
/
Prognostic_studies
Limits:
Adult
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Humans
/
Male
Language:
En
Journal:
Korean Journal of Ophthalmology
Year:
2009
Type:
Article