Role of long non - coding RNA in the pathogenesis of diabetic retinopathy / 国际眼科杂志(Guoji Yanke Zazhi)
International Eye Science
;
(12): 1852-1855, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-641059
ABSTRACT
Long non-coding RNA ( LncRNA) is a class of transcript (>200 nucleotides) that do not encode proteins. It plays an important role in epigenetic regulation and gene expression at transcriptional or post transcriptional level. The abnormal expression of LncRNA may lead to various pathological processes. Diabetic retinopathy ( DR ) is a multifactorial disease. Recent studies have shown that many specific expressions of LncRNAs are closely related to the genesis of DR. In this review, we summarized the recent advances in the function of LncRNA, the regulatory mechanisms of LncRNA involved in the development of DR, and the related therapies.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
Language:
Chinese
Journal:
International Eye Science
Year:
2017
Type:
Article
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