Duane's retraction syndrome and karyotypic abnormalities / 国际眼科杂志(Guoji Yanke Zazhi)
International Eye Science
;
(12): 1747-1748, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-641564
ABSTRACT
AIM:
TO evaluate chromosome 8 abnormalities in Duane's retraction syndrome(DRS)type 1.METHODS:
We evaluated chromosome 8 abnormalities in 29 consecutive cases of DRS type Ⅰ.DNA was isolated from the peripheral leukocytes of patients using a genomic DNA extraction kit,then D8S553 and D8S1797 markers used for polymerase chain reaction(PCR).RESULTS:
None of the cases were positive for the two markers D8S553 and D8S1797 on chromosome 8 which were tested in our study.CONCLUSION:
The possible cause of this finding is that DRS in our patients is more commonly sporadic rather than familial.We recommend study with more cases,other markers,and different chromosomes.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Eye Science
Year:
2008
Type:
Article
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