Effect of phacoemulsification on corneal endothelium of cataract with lupus nephritis / 国际眼科杂志(Guoji Yanke Zazhi)

ABSTRACT

To evaluate the influence of phacoemulsification on corneal endothelium of senile cataract with lupus nephritis (LN). ●METHODS:This clinical trial involved 40 cataract patients with lupus nephritis (40 eyes), and 50 cases (50 eyes) without lupus nephritis. All of them underwent phacoemulsification+lOL implantation. The parameters of corneal endothelial cell including central corneal endothelium cell density ( CED ), average area of endothelial cell ( AVE) and coefficient of variation ( CV) were recorded by corneal endothelial microscope pre -operation and at one month after operation. The data were analyzed by SPSS 13. 0 statistical software. ● RESULTS: Both LN group and control group, the morphology of coneal endothelial was statistical significant differences between pre - operation and 1mo postoperation. The CED was lower, AVE and CV were higher ( P ● CONCLUSlON The corneal endothelial cell in lupus nephritis patients is more fragile. Safe and reliable operation should be selected for these patients.