When should human papillomavirus (HPV) testing be done after conization? / 대한산부인과학회지
Korean Journal of Obstetrics and Gynecology
;
: 1446-1454, 2006.
Article
in English
| WPRIM
| ID: wpr-64303
ABSTRACT
OBJECTIVE:
To know when human papillomavirus (HPV) testing should be done after conization.METHODS:
Between 1997 to 2004, Large Loop Excisions of the Transformation Zone (LLETZ) were done for conization to women with cervical pathology at A University Hospital. The Pap and HPV typing were done before LLETZ procedures. After conizations, HPV typing were planned to be done every 3 months. Every HPV typing was done by HPV oligonucleotide microarray (Biomedlab Co., Seoul, South Korea).RESULTS:
For 8 years, 120 LLETZ were enrolled in this study. There were 8 cases of no neoplasm, 9 cases of CIN 1, 17 cases of CIN 2, 74 cases of CIN 3, 10 cases of microinvasive cervix cancer, and 2 cases of adenocarcinoma in situ. HPV DNA before LLETZ procedures was found about 85.0% and subtype 16 was the most common type among the patients with cervical lesion (40.8%). After LLETZ, 190 HPV typing were done through 1,307 total months (average, 6.9 months/typing). 95 (79.2%) cases had negative results, and 25 (20.8%) cases had positive results. Our data showed that, after conization, about 80% turned out to negative in 6 months.CONCLUSION:
Our data suggested HPV DNA testing should be done after 6 months of LLETZ, as about 80% were destined to negative in 6 months.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
DNA
/
Adenocarcinoma
/
Uterine Cervical Neoplasms
/
Conization
/
Oligonucleotide Array Sequence Analysis
/
Human Papillomavirus DNA Tests
/
Seoul
Limits:
Female
/
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Korean Journal of Obstetrics and Gynecology
Year:
2006
Type:
Article
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