Cutaneous Adverse Effects Associated with Iressa(R)(Gefitinib) Medication / 대한피부과학회지
Korean Journal of Dermatology
;
: 92-95, 2005.
Article
in Korean
| WPRIM
| ID: wpr-64501
ABSTRACT
We report cutaneous adverse effects developed in three patients and are probably related to Iressa(R)(Gefitinib, ZD1839) medication. Iressa(R) is a new anti-cancer agent which acts by inhibiting epidermal growth factor (EGF) receptor signal transduction. The three patients had all taken Iressa(R) for treatment of non-small cell lung cancer and came to our clinic with cutaneous adverse effects. All three patients had acneiform eruptions, and one of the patients also had periungal granulation lesions. Histopathologically, periadnexal inflammatory cellular infiltrations were seen in the acneiform lesions of the three patients and granulation-like tissue proliferations in periungal granulation lesions of the one patient.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Signal Transduction
/
Acneiform Eruptions
/
Carcinoma, Non-Small-Cell Lung
/
Epidermal Growth Factor
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2005
Type:
Article
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