Olfactory Functional MRI Using Echo Planar Imaging Methods / 대한이비인후과학회지
Korean Journal of Otolaryngology - Head and Neck Surgery
;
: 1293-1298, 1997.
Article
in Korean
| WPRIM
| ID: wpr-645583
ABSTRACT
BACKGROUND:
Various olfactory tests have already been proposed in order to clinically assess the olfactory function, for example, UPSIT, T & T olfactometer, CCCRC test, GITU, IV olfaction test. At recent, electro-olfactogram(EOG), olfactorhinometry, olfactory evoked potential, contingent negative variation was tried as the objective olfactory test.OBJECTIVES:
We use the functional imaging of MRI which affords the potential for exploring regional pathophysiologic change in living brain as an olfactory function test. MATERIALS ANDMETHODS:
Functional MRI scans of the brain were performed on 5 healthy subjects and 3 patients with olfactory dysfunction. 2 of the patients were diagnosed Parkinson's disease and the other one had basal skull fracture. Then, all subjects were performed CCCRC test.RESULT:
6 of 8 subjects showed significant region of activation in olfactory bulb and tract. Additional region of activation were also observed in amygdala and parahippocampus. Average activation ratio was 3.42+/-2.37%.CONCLUSION:
These studies indicate that functional MRI have many limitations but it may be used to evaluate olfactory dysfunction and predict prognosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Olfactory Bulb
/
Parkinson Disease
/
Prognosis
/
Skull Fractures
/
Smell
/
Brain
/
Magnetic Resonance Imaging
/
Echo-Planar Imaging
/
Contingent Negative Variation
/
Evoked Potentials
Type of study:
Prognostic study
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Otolaryngology - Head and Neck Surgery
Year:
1997
Type:
Article
Similar
MEDLINE
...
LILACS
LIS