Carbonic anhydrase II immunostaining in the cerebellum of postnatal mice / 대한해부학회지
Korean Journal of Anatomy
;
: 535-541, 1999.
Article
in Korean
| WPRIM
| ID: wpr-646300
ABSTRACT
The carbonic anhydrase II (CA-II) is specifically expressed in oligodendrocytes, the cells responsible for myelination in the central nervous system. However no direct evidence on relationship between myelin formation and CA-II immunoreactivity has been described. The aims of these studies are to investigate the relationship between CA-II and myelination during cerebellar development of mouse. Myelin staining was found on postnatal (P) 14, and its intensity increased in proportion to developmental age. CA-II positive oligodendrocytes were observed in the white matter of cerebellum on P 14 day. CA-II positive oligoden-drocytes also occured in the granular layer and Purkinje cell layers in the later stage of dvelopment. The parallel development in the CA-II expression and myelination during development suggests that CA-II in oligoendrocyte play a role to myelination.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Carbon
/
Central Nervous System
/
Cerebellum
/
Oligodendroglia
/
Carbonic Anhydrases
/
Carbonic Anhydrase II
/
Myelin Sheath
Limits:
Animals
Language:
Korean
Journal:
Korean Journal of Anatomy
Year:
1999
Type:
Article
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