Your browser doesn't support javascript.
loading
Changes in the Regional Cerebral Blood Flow in Postlingual Deaf Patients Measured by ECD-SPECT: Preliminary Study / 대한이비인후과학회지
Article in Ko | WPRIM | ID: wpr-646873
Responsible library: WPRO
ABSTRACT
BACKGROUND AND OBJECTIVES: Cochlear implantation improves hearing ability in adults with profound deafness. Using non-invasive functional brain imaging methods, it is now possible to assess regional blood flow and activity of auditory cortex which might be correlated to the outcome of cochlear implantation. The aim of this study was to measure the regional cerebral blood flow in patients with postlingual deafness utilizing controls in a variety of methods. SUBJECTS AND METHOD: Six postlingual deaf adults who were planned to undertake cochlear implantation and 12 normal controls were examined with technetium-99m-labeled ethyl cysteinate dimer single-photon emission computed tomography (99mTc-ECD-SPECT). Images of the regional cerebral blood flow were processed by statistical parametric mapping and analyzed by unpaired t-test. RESULTS: The analysis of the SPECT images of the 6 deaf patients showed decreased cerebral blood flow in both superior, middle temporal and inferior prefrontal lobes compared with controls (p<0.001). Also this decreased auditory cortical blood flow was greater in left hemisphere in all patients. CONCLUSION: The degree of remaining activity of auditory cortex and the lateralization of the dominant auditory hemisphere, which may influence on the outcome of cochlear implantation, could be measured by ECD-SPECT.
Subject(s)
Key words
Full text: 1 Index: WPRIM Main subject: Regional Blood Flow / Auditory Cortex / Tomography, Emission-Computed / Tomography, Emission-Computed, Single-Photon / Cochlear Implants / Cochlear Implantation / Cystine / Deafness / Functional Neuroimaging / Hearing Limits: Adult / Humans Language: Ko Journal: Korean Journal of Otolaryngology - Head and Neck Surgery Year: 2009 Type: Article
Full text: 1 Index: WPRIM Main subject: Regional Blood Flow / Auditory Cortex / Tomography, Emission-Computed / Tomography, Emission-Computed, Single-Photon / Cochlear Implants / Cochlear Implantation / Cystine / Deafness / Functional Neuroimaging / Hearing Limits: Adult / Humans Language: Ko Journal: Korean Journal of Otolaryngology - Head and Neck Surgery Year: 2009 Type: Article