Gene Therapy for Bone Tissue Engineering
Tissue Engineering and Regenerative Medicine
;
(6): 111-125, 2016.
Article
in English
| WPRIM
| ID: wpr-646906
ABSTRACT
Gene therapy holds a great promise and has been extensively investigated to improve bone formation and regeneration therapies in bone tissue engineering. A variety of osteogenic genes can be delivered by combining different vectors (viral or non-viral), scaffolds and delivery methodologies. Ex vivo & in vivo gene enhanced tissue engineering approaches have led to successful osteogenic differentiation and bone formation. In this article, we review recent advances of gene therapy-based bone tissue engineering discussing strengths and weaknesses of various strategies as well as general overview of gene therapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Osteogenesis
/
Regeneration
/
Bone and Bones
/
Genetic Therapy
/
Bone Morphogenetic Proteins
/
Tissue Engineering
Language:
English
Journal:
Tissue Engineering and Regenerative Medicine
Year:
2016
Type:
Article
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