Lipid Profile in Patients with Osteonecrosis of the Femoral Head / 대한정형외과학회잡지
The Journal of the Korean Orthopaedic Association
;
: 1059-1065, 1999.
Article
in Korean
| WPRIM
| ID: wpr-647625
ABSTRACT
PURPOSE:
Many articles have proposed that osteonecrosis of the femoral head (ONFH) is caused by fat embolism or intravascular coagulation linked to hyperlipidemia. To determine whether hyperlipidemia is an associated factor for ONFH, serum lipid levels were measured. MATERIALS ANDMETHODS:
Nighty-eight patients presenting with ONFH and 110 controls were investigated. We compared the average value of serum lipid levels and the incidence of hyperlipidemia of the two groups.RESULTS:
ONFH group showed generalized increase in lipid level and statistically significant difference in the average value of total cholesterol (P=0.0001), HDL-cholesterol (P=0.0261) and phospholipid (P=0.0465) compared with the control. The incidence of hyperlipidemia of the two groups showed statistically significant difference in HDL-cholesterol (P=0.019) and triglyceride (P=0.024).CONCLUSION:
Hyperlipidemia seems to be associated with pathogenesis of ONFH. We speculated that hyperlipidemia might be a contributing factor of ONFH. Hyperlipidemia may play a role as a triggering factor in the pathogenetic process that results in osteonecrosis. However, it can not be ruled out that secondary hyperlipidemia might be a finding following ONFH.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Osteonecrosis
/
Triglycerides
/
Cholesterol
/
Incidence
/
Embolism, Fat
/
Head
/
Hyperlipidemias
Type of study:
Incidence study
/
Prognostic study
Limits:
Humans
Language:
Korean
Journal:
The Journal of the Korean Orthopaedic Association
Year:
1999
Type:
Article
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