Effects of Soy Protein and Isoflavones on Bone Mineral Density in Crowing Female Rats
The Korean Journal of Nutrition
;
: 359-367, 2003.
Article
in Korean
| WPRIM
| ID: wpr-647909
ABSTRACT
The purpose of this study was to examine the impact of soy protein and soy isoflavones on bone and mineral density in young female Sprague-Dawley rats. Fifty eight rats (body Weight 75+/-5 g) were randomly assigned to one of four groups, consuming casein, soy protein concentrate, soy protein isolate (57 mg isoflavones/100 g diet) or casein added isoflavones (57 mg isoflavones /100 g diet). All rats were fed on experimental diet and deionized water ad libitum for 9 weeks. Bone mineral density (BMD) and bone mineral content (BMC) were measured using PIXImus (GE Lunar Co, Wisconsin, USA) in spine and femur on 3, 6, 9 weeks after feeding. The serum and urine concentrations of Ca and P were determined. Diet did not affect weight gain and mean food intake. Food efficiency ratio was lower In soy protein groups. The serum concentration of Ca and P were not changed by soy protein and isoflavones. Urinary Ca and P excretion were not significantly different. Spine BMD was significantly increased by soy protein isolate on 3 and 6 weeks after feeding. Femur BMD was significantly increased in the groups of soy protein isolate and isoflavones adding on after 9 weeks. Therefore, soy protein with rich isoflavones may be beneficial on spine and femur BMD increasement in growing female rats.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Spine
/
Water
/
Weight Gain
/
Caseins
/
Bone Density
/
Wisconsin
/
Rats, Sprague-Dawley
/
Soybean Proteins
/
Crows
/
Diet
Limits:
Animals
/
Female
/
Humans
Country/Region as subject:
North America
Language:
Korean
Journal:
The Korean Journal of Nutrition
Year:
2003
Type:
Article
Similar
MEDLINE
...
LILACS
LIS