A Case of Gianotti-Crosti Syndrome after Hepatitis A Vaccination / 대한피부과학회지

ABSTRACT

Gianotti-Crosti syndrome (GCS) is a relatively common skin disorder characterized by a distinctive, self-limiting, non-recurrent erythematous or skin-colored papulovesicular eruption. It mainly affects the extremities, buttocks and face. It commonly occurs in infants, young children and, infrequently, in adults. GCS following immunization has already been described with DTP, MMR, BCG, oral polio and influenza vaccinations. We report a case of GCS in an 18 month-old boy. He had suffered from symmetrical, flat-topped, erythematous papules on the face, buttocks, and extensor surfaces of extremities for 10 days. He had received a hepatitis A vaccination 1 month ago. Otherwise, there was no noticeable past history. The viral markers were all negative and other laboratory findings including liver function tests were within normal range. The skin lesions disappeared after conservative treatment. We, herein, report a case of GCS, of which hepatitis A vaccination might be a possible cause.