Hematologic parameters to predict negative cerebrospinal fluid examination results among neurologically intact patients who underwent lumbar puncture on suspicion of central nervous system infection
Clinical and Experimental Emergency Medicine
;
(4): 25-31, 2017.
Article
in English
| WPRIM
| ID: wpr-648380
ABSTRACT
OBJECTIVE:
Cerebrospinal fluid (CSF) examination is mandatory whenever central nervous system (CNS) infection is suspected. However, pleocytosis is not detected in a substantial number of suspected patients who undergo CSF examination. This study aimed to identify parameters that can aid in predicting negative CSF examination results (defined as a white blood cell count of 0.7, and the best cutoff values were 6.0 (accuracy 70.3%) and 12.7 mg/L (accuracy 76.2%), respectively.CONCLUSION:
The neutrophil-to-lymphocyte ratio ≥6 and C-reactive protein level ≥12.7 mg/L was significantly associated with negative CSF examination result.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Spinal Puncture
/
C-Reactive Protein
/
Lymphocytes
/
Central Nervous System
/
Central Nervous System Infections
/
Cerebrospinal Fluid
/
Hematologic Tests
/
Leukocyte Count
/
Leukocytes
/
Leukocytosis
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
Clinical and Experimental Emergency Medicine
Year:
2017
Type:
Article
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