Severe Fever with Thrombocytopenia Syndrome / 대한구급학회지
The Korean Journal of Critical Care Medicine
;
: 59-63, 2014.
Article
in English
| WPRIM
| ID: wpr-649995
ABSTRACT
Severe fever with thrombocytopenia syndrome (SFTS) is a newly emerging infectious disease, caused by a novel species of Phlebovirus of Bunyaviridae family, in China, South Korea, and Japan. SFTS is primarily known as a tick-borne disease, and human-to-human transmission is also possible in contact with infectious blood. Common clinical manifestations include fever, thrombocytopenia, and leukopenia as initial symptoms, and multiple organ dysfunction and failure manifest with disease progression. Whereas disease mortality is reported to be 12% to 30% in China, a recent report of cumulative SFTS cases indicated 47% in Korea. Risk factors associated with SFTS were age, presence of neurologic disturbance, serum enzyme levels, and elevated concentrations of certain cytokines. Diagnosis of SFTS is based on viral isolation, viral identification by polymerase chain reaction, and serologic identification of specific immunoglobulin G. Therapeutic guideline has not been formulated, but conservative management is the mainstream of treatment to prevent disease progression and fatal complications.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Thrombocytopenia
/
Bunyaviridae
/
Immunoglobulin G
/
China
/
Polymerase Chain Reaction
/
Risk Factors
/
Mortality
/
Cytokines
/
Phlebovirus
/
Tick-Borne Diseases
Type of study:
Diagnostic study
/
Etiology study
/
Practice guideline
/
Prognostic study
/
Risk factors
Limits:
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
The Korean Journal of Critical Care Medicine
Year:
2014
Type:
Article
Similar
MEDLINE
...
LILACS
LIS