A Case of Giant Keratoacanthoma of the Lower Lip Treated with Intralesional Methotrexate / 대한이비인후과학회지
Korean Journal of Otolaryngology - Head and Neck Surgery
;
: 1858-1862, 1997.
Article
in Korean
| WPRIM
| ID: wpr-650855
ABSTRACT
Keratoacanthoma(KA) is a rapidly growing benign cutaneous neoplasm, usually occurring on sunexposed sites in elderly people, and it has a close clinical and pathologic resemblance to squamous cell carcinoma. Giant KA of the lower lip is extremely rare. Various treatment modalities have been reported including radiation therapy, systemic oral retinoids, and the intralesional application of 5-fluorouracil(5-FU), methotrexate(MTX) or interferon alpha-2a. Excisional surgery, however, remains the treatment of choice for the majority of KA. The disadvantages of excision are the possible requirement for extensive reconstructive surgery and the resultant cosmetic or functional deficit. Recently, we experienced a case of giant KA of the lower lip in a 60-year-old male, and he was treated successfully with intralesional methotrexate. Now we report the case with a brief review of literature.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Retinoids
/
Carcinoma, Squamous Cell
/
Methotrexate
/
Interferons
/
Keratoacanthoma
/
Lip
Limits:
Aged
/
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Otolaryngology - Head and Neck Surgery
Year:
1997
Type:
Article
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