A Case of Recurrent Eosinophilic Granuloma in the Maxilla / 대한이비인후과학회지

ABSTRACT

Langerhans cell histiocytosis is global term for a spectrum of diseases which include eosinophilic granuloma, Hand-Schuller-Christian disease and Letterer-Siwe disease. Eosinophilic granuloma of bone usually presents as a solitary lytic lesion and responds well to conservative treatment. It may involve the femur, humerus, ribs, and other bones, but is most common in the skull and jaws, and it may be solitary or multifocal the latter form is more likely to recur or be associated with systemic disease. In the maxillofacial region, the disease may present in a variety of ways including swelling, bone pain, gingival inflammation, ulceration, mobile teeth and even pathological fracture. Treatment of this disease usually requires a multidisciplinary approach. In cases of solitary bone lesion, surgery is indicated as the first treatment modality. All other disease situations with multiple organ involvement or multiple bone lesions usually requires multiple surgical as well as non-surgical interventions, such as chemotherapy and radiotherapy. We report, with a review of literature, a case of recurrent eosinophilic granuloma of the maxilla, the patient have presented a history of previous eosinophilic granuloma with skull lesion teated by craniectomy.