Long-Term Follow-Up of Immunotherapy in Allergic Rhinitis to House Dust Mite / 대한이비인후과학회지
Korean Journal of Otolaryngology - Head and Neck Surgery
;
: 1006-1011, 2007.
Article
in Korean
| WPRIM
| ID: wpr-652683
ABSTRACT
BACKGROUND AND OBJECTIVES:
This study was to evaluate the long-term effect of immunotherapy on the allergic rhinitis patients to house dust mite (HDM) patients. SUBJECTS ANDMETHOD:
Sixty-five patients were treated for allergic rhinitis in the allergy clinic. Every patient underwent immunotherapy for 3 to 5 years and did not receive any additional treatments after the completion of the initial one. The survey on the symptom improvement and the patients' satisfaction was carried out 3 and 10 years after the immunotherapy treatment. The results of skin prick test for each individual were analyzed before, 3 and 10 years after the immunotherapy, respectively.RESULTS:
Overall symptom improvement surveyed 10 years after the immunotherapy decreased compared with that taken after 3 years of the treatment (p<0.05). In particular, symptom improvements on sneezing, itching sensation, and rhinorrhea was significantly decreased after 10 years (p<0.05). Patients' satisfaction level was 64.6% after 3 years and 49.2% after 10 years of the immunotherapy treatment. Skin prick test reactivity was significantly decreased after 3 years of the treatment compared to before the treatment. Although skin prick test reactivity measured in 10 years after immunotherapy increased compared with that measured in 3 years after, there was little statistical significance when compared with the reactivity before the treatment.CONCLUSION:
The immunotherapy has long term efficacy on allergic rhinitis to HDM. However, the efficacy decreased after the discontinuance of the immunotherapy treatment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Personal Satisfaction
/
Pruritus
/
Sensation
/
Skin
/
Sneezing
/
Rhinitis
/
Follow-Up Studies
/
Pyroglyphidae
/
Dust
/
Hypersensitivity
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Otolaryngology - Head and Neck Surgery
Year:
2007
Type:
Article
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