The Effectiveness of C-Reactive Protein Surveillance as a Method to Monitor the Post-Operative Antibiotics Administration after Total Knee Replacement Arthroplasty / 대한정형외과학회잡지
The Journal of the Korean Orthopaedic Association
;
: 171-177, 2012.
Article
in Korean
| WPRIM
| ID: wpr-652705
ABSTRACT
PURPOSE:
To evaluate the effectiveness of using C-reactive protein (CRP) surveillance as a method to monitor the effect of postoperative antibiotics for the prevention of early infection after total knee replacement arthroplasty (TKRA). MATERIALS ANDMETHODS:
A prospective study was performed in 115 primary TKRAs. We examined the values of CRP of all cases on the 3rd, 5th, 7th, 10th and 14th days post-operatively. Some patients were administrated additional antibiotics under certain specific situations based on the pattern of CRP. The patients were divided into two groups group I with planned period of administration and group II with administration longer than the planned period.RESULTS:
No acute infection after TKRA due to CRP surveillance was observed. The mean duration of antibiotics administration was 5.9 days in all cases, 5 days in group I and 13.3 days in group II. Twelve cases (10.4%) were included in group II. The CRP was increased on the 5th and 10th days after operation in group II.CONCLUSION:
The surveillance of CRP was thought to be helpful in monitoring the effects of post-operative antibiotics and prevention of early infection after TKRA.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Organothiophosphorus Compounds
/
Arthroplasty
/
C-Reactive Protein
/
Prospective Studies
/
Antibiotic Prophylaxis
/
Arthroplasty, Replacement, Knee
/
Knee
/
Anti-Bacterial Agents
Type of study:
Observational study
/
Screening study
Limits:
Humans
Language:
Korean
Journal:
The Journal of the Korean Orthopaedic Association
Year:
2012
Type:
Article
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