Peripheral Primitive Neuroectodermal Tumor with Osseous Component of the Small Bowel Mesentery: A Case Study
Korean Journal of Pathology
;
: 77-81, 2013.
Article
in English
| WPRIM
| ID: wpr-65405
ABSTRACT
A case of peripheral primitive neuroectodermal tumor of the small bowel mesentery with osseous component is reported. A 23-year-old man was admitted to our hospital because of acute severe abdominal pain. Abdominal computed tomography revealed a large solid and cystic, oval shaped mass, measuring 11.0x6.0 cm in the pelvic cavity. Histologically the resected lesion consisted of sheets of undifferentiated small round cells forming Homer-Wright rosettes and perivascular pseudorosettes, and showed areas of osteoid and bone formation. Immunohistochemical studies revealed that tumor cells expressed positivity against CD99 (MIC2), CD57, neuron-specific enolase, and vimentin. Fluorescence in situ hybridization study revealed Ewing sarcoma breakpoint region 1 (EWSR1) gene rearrangement on chromosome 22q12. To the authors' knowledge this is the first documentation of a peripheral neuroectodermal tumor with osteoid and bone formation of the small bowel mesentery.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Osteogenesis
/
Phosphopyruvate Hydratase
/
Sarcoma, Ewing
/
Vimentin
/
Gene Rearrangement
/
Abdominal Pain
/
In Situ Hybridization
/
Neuroectodermal Tumors, Primitive
/
Neuroectodermal Tumors, Primitive, Peripheral
/
Fluorescence
Language:
English
Journal:
Korean Journal of Pathology
Year:
2013
Type:
Article
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