Propofol-Related Infusion Syndrome in an Adult Patient Using Propofol Coma Therapy to Control Intracranial Pressure / 대한구급학회지
The Korean Journal of Critical Care Medicine
; : 234-238, 2013.
Article
in Ko
| WPRIM
| ID: wpr-655433
Responsible library:
WPRO
ABSTRACT
Propofol-related infusion syndrome (PRIS) is a rare but fatal complication. Unexplained metabolic acidosis, rhabdomyolysis, hyperkalemia, myocardial dysfunction, cardiovascular collapse and acute kidney injury are the main characteristics of PRIS. Herein, we report a case of PRIS in a neurosurgical adult patient, who had received high-dose propofol continuous infusion in order to control intracranial pressure in an intensive care unit. She manifested severe metabolic acidosis, rhabdomyolysis, acute kidney injury and myocardial dysfunction. As soon as PRIS was diagnosed, propofol infusion was stopped. Conservative treatments, such as vasopressors and inotropics, continuous renal replacement therapy and extracorporeal membrane oxygenation were used to treat PRIS. However, she finally expired. This case report suggests that a great caution to PRIS is needed in a situation with high-dose propofol continuous infusion.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Rhabdomyolysis
/
Acidosis
/
Extracorporeal Membrane Oxygenation
/
Intracranial Pressure
/
Propofol
/
Renal Replacement Therapy
/
Coma
/
Acute Kidney Injury
/
Hyperkalemia
/
Intensive Care Units
Limits:
Adult
/
Humans
Language:
Ko
Journal:
The Korean Journal of Critical Care Medicine
Year:
2013
Type:
Article