A Typical Case of IgG4-related Ophthalmic Disease Satisfying Diagnostic Criteria
Journal of the Korean Ophthalmological Society
;
: 852-856, 2017.
Article
in Korean
| WPRIM
| ID: wpr-65564
ABSTRACT
PURPOSE:
In the present study, a case of IgG4-related ophthalmic disease which met the 2015 IgG4-related ophthalmic disease diagnostic criteria is reported and literature review performed. CASESUMMARY:
A 51-year-old female presented with both upper eyelid swelling, redness, and a palpable mass. Eye movements were normal and exophthalmos was not observed. Facial computed tomography showed both lacrimal gland hypertrophy. The patient underwent left anterior orbitotomy with incisional biopsy. Immunostained biopsy showed the ratio of IgG4+ to IgG+ cells was 50% and the mean number of IgG4-positive plasma cells was approximately 150 per high-power field. Hematological examination showed elevated serum IgG4 concentrations of 6,930 mg/dL, however, other organs were not involved. The patient satisfied the diagnostic criteria for IgG4-related ophthalmic disease. The patient was given an oral steroid and immunosuppressant and the symptoms improved.CONCLUSIONS:
IgG4-related ophthalmic disease is currently receiving increased attention. The authors of the present study report a case of IgG4-related ophthalmic disease which met the 2015 IgG4-related ophthalmic disease diagnostic criteria.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plasma Cells
/
Biopsy
/
Immunoglobulin G
/
Exophthalmos
/
Eye Movements
/
Eyelids
/
Hypertrophy
/
Lacrimal Apparatus
Type of study:
Diagnostic study
Limits:
Female
/
Humans
Language:
Korean
Journal:
Journal of the Korean Ophthalmological Society
Year:
2017
Type:
Article
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