Prognostic Factors of Nasal NK/T Cell Lymphoma / 대한이비인후과학회지
Korean Journal of Otolaryngology - Head and Neck Surgery
;
: 37-42, 2007.
Article
in Korean
| WPRIM
| ID: wpr-656160
ABSTRACT
BACKGROUND AND OBJECTIVES:
Nasal natural killer T (NK/T) cell lymphomas are relatively common in Asia, but the prognostic factors are not well known. The purpose of this research was therefore to evaluate those prognostic factors. SUBJECTS ANDMETHOD:
We reviewed and analyzed the medical records of 68 patients diagnosed as nasal NK/T cell lymphomas between 1984 and 2003 at Ajou University Hospital and at Yonsei University Hospital. Prognostic factors that include age, B symptoms, serum lactate dehydrogenase (LDH) levels, Eastern cooperative oncology group (ECOG) performance status, international prognostic indices (IPI), treatment modality, and Ann Arbor tumor stages were analyzed using the methods of univariate and multivariate statistics.RESULTS:
The five-year overall survival rate was 43%. By univariate analysis, we found ECOG performance status, Ann Arbor tumor stages, B symptoms, and IPI to be significant prognostic factors of nasal NK/T cell lymphoma. The multivariate analysis showed that ECOG performance status and B symptoms were significant.CONCLUSION:
ECOG performance status, Ann Arbor tumor stages, B symptoms, and IPI could all be prognostic factors of the nasal NK/T cell lymphoma. Among these factors, ECOG performance status and B symptoms may be regarded more useful in diagnosis of the disease than others.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Asia
/
Medical Records
/
Multivariate Analysis
/
Survival Rate
/
Diagnosis
/
L-Lactate Dehydrogenase
/
Lymphoma
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Korean Journal of Otolaryngology - Head and Neck Surgery
Year:
2007
Type:
Article
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