A Case of Thyroid Granular Cell Tumor / 대한이비인후과학회지

ABSTRACT

Granular cell tumor is an uncommon neoplasm that can occur everywhere in the human body. Granular cell tumor of the thyroid gland is very rare and only eight cases of thyroid granular cell tumor have been reported. Histopathologically, granular cell tumor consists of large polygonal cells with small dark nuclei and abundant, fine, granular eosinophilic cytoplasm that show positive immunohistochemical staining using S-100 protein. Surgical excision is the treatment of choice for granular cell tumor. Recurrence is rare, but inadequate resection of granular cell tumor may cause local recurrence. We have experienced one case of thyroid granular cell tumor that we report here with a review of literatures.