Treatment Outcomes of Olfactory Neuroblastoma: A Report of 5 Cases / 대한이비인후과학회지
Korean Journal of Otolaryngology - Head and Neck Surgery
;
: 1562-1566, 1998.
Article
in Korean
| WPRIM
| ID: wpr-656829
ABSTRACT
BACKGROUND AND OBJECTIVES:
Several strategies have been reported for the treatment of olfactory neuroblastoma such as radiation therapy, chemotherapy, craniofacial resection, or their combination. However, a consensus regarding the optimal management has not been obtained. In this study, we examined the outcomes of different treatment modalities in five patients with olfactory neuroblastoma. MATERIAL ANDMETHOD:
Five patients diagnosed as olfactory neuroblastoma during the past 10 years were retrospectively analyzed.RESULTS:
Five patients were categorized by the modified Kadish's staging system. Three patients underwent surgery. Radiotherapy was given concurrently with chemotherapy for two patients. Distant metastases were observed in two cases, one in the heart and the other in the cervical lymph node. After a median follow-up of 34 (12-87) months, two patients who underwent craniofacial resection only and another two patients who received combined radiotherapy and chemotherapy are still alive. One patient who underwent Denker's operation with postoperative radiotherapy had died of heart failure as a result of cardiac metastasis.CONCLUSION:
We suggest a complete surgical resection as a primary treatment modality, however, a multi-drug chemotherapy with radiotherapy could be the choice of treatment in cases of children or one with distant metastasis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Radiotherapy
/
Retrospective Studies
/
Follow-Up Studies
/
Treatment Outcome
/
Esthesioneuroblastoma, Olfactory
/
Consensus
/
Drug Therapy
/
Heart
/
Heart Failure
/
Lymph Nodes
Type of study:
Practice guideline
/
Observational study
/
Prognostic study
Limits:
Child
/
Humans
Language:
Korean
Journal:
Korean Journal of Otolaryngology - Head and Neck Surgery
Year:
1998
Type:
Article
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