Expression and significance of UAlb/Cr ,eGFR ,SCr and Cys-C in H-type hypertension patients with early kidney damage / 国际检验医学杂志

ABSTRACT

Objective To study the expression and significance of urinary albumin/creatinine (UAlb/Cr) ,glomerular filtration rate (eGFR) ,serum creatinine (SCr) and cystatin C (Cys-C) in H-type hypertension patients with early renal damage .Methods Totally 130 cases of H-type hypertensive patients from July 2015 to June 2016 in this hospital was conducted .According to glomer-ular filtration rate (GFR) ,those patients were divided into normal renal function group (n=62 ,GFR≥90 mL/L) and kidney dam-age group (n=73 ,GFR<90 mL/L) .Cys-C was detected by latex turbidimetry and UAlb/Cr ,SCr was detected by creatine oxidase method ,MDRD were used to calculate eGFR .The expression of UAlb/Cr ,eGFR ,SCr and Cys-C were analyzed ,and the risk factors of UAlb/Cr and eGFR were analyzed by Logistic regression analysis .Results The levels of UAlb/Cr ,SCr and Cys-C in normal re-nal function group were lower than those in kidney damage group (P<0 .05) ,and the level of eGFR was significantly higher than that of kidney damage group (P<0 .05) .Age ,course of disease ,Hcy ,DBP were closely related to UAlb/Cr(P<0 .05) .Age ,course of disease ,Hcy were closely related to eGFR (P<0 .05) .Conclusion The expression of UAlb/Cr ,eGFR ,SCr and Cys-C is closely related to H-type hypertension patients with early kidney damage .