Clinical effects of Mupirocin ointment combined with topical glucocorticoid drugs in the treatment of eczema/atopic dermatitis / 中国生化药物杂志

ABSTRACT

Objective To analyze clinical effects of Mupirocin ointment combined with topical glucocorticoid drugs in treating eczema/atopic dermatitis. Methods 100 patients with eczema / atopic dermatitis patients treated in our hospital from March 2015 to August 2016 were selected and randomly divided into the control group and the experimental group, 50 patients in each group. The control group were treated with glucocorticoid therapy, the experimental group were treated with topical corticosteroids combined with Mupirocin ointment drug. Compared the clinical effect between two groups. Results After treatment, 7 cases relapsed in the experimental group and 17 relapsed in the control group.The recurrence rate of the control group(34.0%)was significantly higher than that of the experimental group (14.0%),there was significantly statistical difference(P<0.05). There were no obvious adverse reactions in two groups. In the experimental group, 8 cases were ineffective, and the total effective number was 42 cases. In the control group, 20 cases were ineffective, and the total effective number was 30 cases. The effective rate of the control group (60.0%) was significantly lower than that of the experimental group(84.0%), there was significantly statistical difference (P<0.05). Conclusion Mupirocin ointment combined with topical glucocorticoid drugs was good clinical effect and low adverse reactions.