Effect of clozapine treatment and rehabilitation nursing on social dysfunction of schizophrenia / 中国生化药物杂志

ABSTRACT

Objective To study and analyze the effect of clozapine treatment and rehabilitation nursing on social dysfunction of schizophrenia. Methods 88 patients with schizophrenia in Tongde Hospital were selected as the subjects. The control group was treated with clozapine, with an initial dose of 50 mg, once a day. On the basis of the experimental group received rehabilitation nursing measures, health education, establishing harmonious doctor-patient relationship, according to the actual situation of patients received psychological counseling measures, pay attention to patients with mood changes, the patients were encouraged to manual labor and rehabilitation activities. Results Before treatment, the scores of social function disability screening scale of the experimental group and the control group were (6.89±1.65) points and (6.57±1.63) points, and the difference between the two groups was not statistically significant. After treatment, the defect score of the experimental group was (4.32 ±1.10), significantly lower than the control group, the scale score was (5.67 ± 1.37), and the difference between the two groups was statistically significant (P<0.05). Conclusion Clozapine combined with rehabilitation nursing in the treatment of schizophrenia social function defects, the clinical efficacy is ideal, can significantly improve the social function defects of patients, and has clinical significance.