Clinical analysis of ligustrazine in the treatment of chronic renal failure / 中国生化药物杂志

ABSTRACT

Objective To investigate the clinical effect of ligustrazine on the treatment of chronic renal failure. Methods 94 patients with chronic renal failure from Oct. 2015 to Jan. 2017 of Taizhou central hospital were randomly divided into two groups the study group (n=47) and the control group (n=47), the control group were received routine clinical treatment, the study group were treated with ligustrazine on the basis of routine treatment. Scr, Ccr, BUN and adverse reaction in the two groups were recorded and compared. Results Scr, Ccr, BUN between the two groups has no statistically difference. After treatment, Scr, Ccr and BUN in the study group were better than those in the control group (P<0.05). There was no significant difference in adverse reactions between the two groups. Conclusion On the basis of routine drug treatment, ligustrazine can significantly improve the clinical efficacy of patients with chronic renal failure, and less adverse reactions.