Buprenorphine fentanyl transdermal system combined gone.love Buna needle in artificial knee joint replacement long-acting analgesic effect / 中国生化药物杂志

ABSTRACT

Objective To study the transdermal buprenorphine Finland combined needle in patients in Buner after total knee arthroplasty long-acting analgesic effect. Methods 60 cases of total knee arthroplasty in Zhoushan Guang'an Hospital from February 2015 to August 2016 were selected as the study subjects, and were randomly divided into the control group and the experimental group, each group had 30 cases. The postoperative patients in control group were given Bouna needle, given buprenorphine finland transdermal patch on the basis of the experimental group. If the visual analogue scale of the two patients was greater than 5, tramadol hydrochloride sustained release tablets was given. The analgesic effects of the experimental group and the control group were compared and analyzed. Results After seventh days of treatment, the resting pain score of the experimental group was (1.11±0.43), significantly lower than that of the control group (2.50±0.68), with statistical significance (P<0.05). Seventh days after treatment, the daily dose of tramadol in the experimental group was (210.09±20.90) mg, significantly less than that of the control group (1123.90±60.90) mg, with statistical significance (P<0.05). There were no obvious adverse reactions in the two groups, and there was no significant difference. Conclusion The application of buprenorphine transdermal patches combined with finland gone.love Buna needle in artificial knee joint replacement surgery, the analgesic effect is obvious, can to some extent reduce the dosage of analgesic, side effects may still need to observe.