Correlation between pathological grade and ultrasonographic features of clear cell renal carcinoma / 医学研究生学报

ABSTRACT

Objective To analyze the correlation between ultrasonographic features and pathological grade of clear cell renal carcinoma(CCRCC). Methods We retrospectively analyzed the conventional ultrasound and contrast enhanced ultrasound in 150 cases of CCRCC from November 2013 to February 2017 which were confirmed by pathology in Institute of Nephrology of Nanjing Gener-al Hospital .Pathological grade was classified into Ⅰ , Ⅱ, Ⅲ,Ⅳ, with 122 cases of low grade CCRCC (grade Ⅰ and grade Ⅱ) and 28 cases of high grade CCRCC ( grade Ⅲ and grade Ⅳ ) .Their correlations with the features of conventional ultrasound and contrast en-hanced ultrasound were analyzed . Results The maximum diameter of the tumor ( low grade40.00 ±16.11, high grade56.43 ± 23.30), the minimum diameter of the tumor(low grade34.73±14.02,high grade45.79±16.17), rate of pseudocapsule displaying [low gradepresence52(74%),absence70(26%);high gradepresence4(14%),absence24(86%)], and the enhanced uniformity [low gradeuniformity 19(16%),Cystic change 95(78%),necrosis 8(6%);high gradeuniformity 5(18%),Cystic change 1(4%), necrosis 22( 78%) ] were related to the pathological grade .Binary logistic regression analysis showed that the main factors related to the pathological grade were the rate of pseudocapsule displaying (OR4.348,95%CI 1.252-15.096)and the enhanced uniformity (OR11.425,95%CI4.326-29.229) Conclusion The characteristics of CCRCC conventional ultrasound and contrast-enhanced ultra-sound were related to the pathological grade , and the main factors were the rate of pseudocapsule displaying and enhanced uniformity .