Development of metabonomics of drug dependence / 中华行为医学与脑科学杂志

ABSTRACT

Drug dependence brings heavy burden to globe medicine and security,however,the mechanism is unclear.And because of the legal question,patients tend to hide their history of drug use,which make the diagnosis difficult.Metabonomics is an emerging system biological technology which can offer a new view about the diseases.This paper reviewed the metabonomics research progress of the main dependence drugs,and proved that metabonomics technology may discover biomarkers for diagnosis and treatment of drug dependence.The relationship between peripheral metabonomics and center nerve system may become an important research field.More information may come from the united apply of genomics,proteomics and metabonomics.Finally,there will be a breakthrough in identification of individuals with susceptibility to drug dependence,and supply a preventive or treatment plan.